749 research outputs found

    Can models of organizational change help to understand ā€˜successā€™ and ā€˜failureā€™ in community sentences? Applying Kotterā€™s model of organizational change to an Integrated Offender Management case study

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    A number of nationally driven initiatives have led to significant changes in the framework of community sentences, with various agencies being required to work in ā€˜joined-upā€™ multi-agency arrangements. Most notable, perhaps, has been the increased working relationship between police and probation, most recently within Integrated Offender Management (IOM). Although these have produced some positive outcomes in relation to crime reduction, success is sporadic and often quite modest. Research has identified a number of barriers to successful implementation, and this article builds on this by drawing upon fresh empirical evidence to argue that the success of such schemes relies on the management of organizational change that will inevitably and necessarily occur. Applying Kotterā€™s model of organizational change to data generated from an evaluation of two IOM schemes in England, the article offers an explanatory account of the implementation of the schemes and the possible effect this had on efforts to reduce crime

    The Problem with Negligence

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    Ordinary morality judges agents blameworthy for negligently produced harms. In this paper I offer two main reasons for thinking that explaining just how negligent agents are responsible for the harms they produce is more problematic than one might think. First, I show that negligent conduct is characterized by the lack of conscious control over the harm, which conflicts with the ordinary view that responsibility for something requires at least some conscious control over it. Second, I argue that negligence is relevantly indistinguishable from inadvertence, which is ordinarily thought to excuse agents from responsibility. I argue that the parallels between negligence and inadvertence suggest that negligent agents are not responsible for the harms they produce, while proposing an alternative model for distinguishing between negligence and inadvertence that does justice to our intuitions

    Tempo- May 20, 1947

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    https://neiudc.neiu.edu/tempo/1021/thumbnail.jp

    Tempo- Jun. 3, 1947

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    https://neiudc.neiu.edu/tempo/1022/thumbnail.jp

    Tempo- Mar. 7, 1947

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    https://neiudc.neiu.edu/tempo/1020/thumbnail.jp

    Tempo- Feb. 18, 1947

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    https://neiudc.neiu.edu/tempo/1019/thumbnail.jp

    A Framework for collaborative writing with recording and post-meeting retrieval capabilities

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    From a HCI perspective, elucidating and supporting the context in which collaboration takes place is key to implementing successful collaborative systems. Synchronous collaborative writing usually takes place in contexts involving a ā€œmeetingā€ of some sort. Collaborative writing meetings can be face-to-face or, increasingly, remote Internet-based meetings. The latter presents software developers with the possibility of incorporating multimedia recording and information retrieval capabilities into the collaborative environment. The collaborative writing that ensues can be seen as an activity encompassing asynchronous as well as synchronous aspects. In order for revisions, information retrieval and other forms of post-meeting, asynchronous work to be effectively supported, the synchronous collaborative editor must be able to appropriately detect and record meeting metadata. This paper presents a collaborative editor that supports recording of user actions and explicit metadata production. Design and technical implications of introducing such capabilities are discussed with respect to document segmentation, consistency control, and awareness mechanisms

    RECOLED: A group-aware collaborative text editor for capturing document history

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    This paper presents a usability analysis of RECOLED, a shared document editor which supports recording of audio communication in remote collaborative writing sessions, and transparent monitoring of interactions, such as editing, gesturing and scrolling. The editor has been designed so that the collaboration results in the production of a multimedia document history which enriches the final product of the writing activity and can serve as a basis for post-meeting information retrieval. A discussion is presented on how post-meeting processing can highlight the usefulness of such histories in terms of tracking information that would be normally lost in usual collaborative editing settings

    Directed Solid Phase Peptide Synthesis of alpha-Conotoxin MII

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    Conotoxinsā€”short, disulfide-rich peptides found in the venom of cone snailsā€”exhibit unprecedented receptor binding selectivity. Ī±-Conotoxin MII (Ī±-CTxMII) targets the Ī±3Ī²2-nicotinic acetylcholine receptor (nAChR) isoform; studying the interaction of this peptide with nAChRs provides an understanding of binding determinants that may benefit therapeutic development for diseases like Alzheimerā€™s and Parkinsonā€™s. Linear peptide was synthesized on solid support RINK resin by automated peptide synthesis followed by cleavage from resin and subsequent oxidative folding to form disulfide bridges. Mass spectral analysis validated proper synthesis and initial fold formation. QTOF-MS (m/z): [M + H]+ calculated for Ī±-CTxMII, 1856.8; found, 928.9, 619.6 which correspond to the doubly and triply charged molecular ions. Next the peptide will be purified by chromatography and again verified using mass spectrometry. Finished product will be used to validate the applicability of PC-12 cells for expression of Ī±3Ī²2-nAChRs
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